Treatment of gonorrhea

The effectiveness of long-acting penicillins (e.g. benzathine benzylpenicillin) with syphilis is not comparative to their use in treatment of gonorrhea.

Phenoxymethylpenicillin, semi-synthetic penicillins, and first generation cephalosporins are not recommended either for the treatment of gonorrhea.

New treatment recommendations published in 1993 by the US Center for Disease Control (CDC) are developed taking into account:

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  • The simplicity and effectiveness of a single dose of the medicine
  • The prevalence of strains resistant to penicillins (including ampicillin and amoxicillin) and tetracyclines (over 30 percent strains in the USA and over 50 percent – in developing countries)
  • The high frequency combination of gonorrhea with chlamydia
  • The severity of complications caused by gonorrhea and chlamydia
E.g., in adults with uncomplicated gonococcal urethritis, gonococcal cervicitis, gonococcal pharyngitis or gonococcal proctitis, a single dose of one of the most effective medications is recommended:
  • Cefixime 400 mg.
  • Ciprofloxacin.
  • Ofloxacin.
  • Azithromycin-Teva.
For the treatment of possible chlamydia, Doxycycline is also given at the same time for 7 days. Doxycycline may be replaced by a single dose of Azithromycin 1 g, which is more convenient and efficient, but is also more expensive. Recommended regimens effectively treat any form of gonococcal infection and concomitant chlamydia.

Home treatment guideline under Dr. Israel Levin online supervision

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A single dose of Azithromycin 2 g is effective for gonorrhea; however, it has important side effects on the digestive system. With gonorrhea, serological tests for syphilis are mandatory, and anonymous HIV testing is also offered. Taking doxycycline for one week in most cases is enough to cure syphilis during the incubation period.

However, if syphilis is detected together with gonorrhea, or if patients with gonorrhea had intercourse with patients who had syphilis, additional treatment is conducted depending on the stage of the syphilis infection.

Observation and strategy to avoid treatment failure

The regimen with ceftriaxone + doxycycline and cefixime are usually as effective as those used in the USA, which are ciprofloxacin + doxycycline and ofloxacin + doxycycline.

The following treatment for gonorrhea is recommended by the specialists of Alishech clinics:

Medicine Number of tablets Number of doses per day Number of days Total tablets
Ofloxacin Teva 200mg (Ofloxacin) 2 1 1 2
Azenil 250 mg (Azithromycin) 4 1 1 4
Doxylin 100 mg 1 2 7 14
Alishech Activator 1 1 10 10
Alishech Probiotic 1 1 30 30

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Gonorrhea: Symptoms, treatment, and causes:

Problems of urinating in men: